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MYP_061227
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Basic Information
pardaxin-6 (GE-6) (Derived from pardaxin)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
27 amino acids
C134H217N29O34
Standard
Sequence
GFFALIPKIISSPLFKTLLSAVGSALS
Physicochemical Analysis
2778.33 Da
10.00
1.76
1.55
0.0651
1.26
0.50
0.49
20.11
137.41
0.1111
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
975.76
-6.31
34.0
36.0
88.0
197.0
5.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0054959 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Vibrio vulnificus
50 μg/mL
MIC
PMID23598079 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598079/
RECORD: Rec_0085595 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID23598079 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598079/
RECORD: Rec_0111520 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pardaxin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Vibrio alginolyticus
12.5 μg/mL
MIC
PMID23598079 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598079/
RECORD: Rec_0131695 VERIFIED: YES
Provenance & Taxonomy
Pardachirus marmoratus [Animal]
Epinephelus nebulosus
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
HeLa
50 μg/mL
Cytotoxicity assay
PaperTruncated antimicrobial peptides from marine organisms retain anticancer activity and antibacterial activity against multidrug-resistant Staphylococcus aureus PMID23598079 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598079/
RECORD: Rec_0137379 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pardaxin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa
12.5 μg/mL
MIC
PMID23598079 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598079/
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