Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length189 amino acids

Chemical FormulaC921H1439N247O253S7

DescriptionStandard

        PTALLGAQEPMVLLAITEFVANSATFVYFTAGALHRNVSADTLPRWFPLQLKTKSMAQFCPKLQELYPDRPMELHLSARRQPLLSCHPDALHGALFGSAEAFVVLPNATRVPAFLLNIDANVTGKPTITGNRLGGTVSLTGGGSALPAPCQAQGLSVPQVKQLETGLKFGLWLFGVPWANSECHPHPVP
    

Molecular Weight20244.24 Da

Isoelectric Point (pI)8.58

Net Charge (pH 7.0)2.46

Net Charge (pH 7.4) 2.01

Charge Density (pH 7.0) 0.0130

GRAVY Index0.13

Hydrophobic Moment 0.51

Boman Index0.18

Instability Index45.00

Aliphatic Index 92.96

Aromaticity 0.0794

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7776.27

LogP -89.85

H-bond Donors 264.0

H-bond Acceptors 268.0

Rotatable Bonds 632.0

Heavy Atoms 1428.0

Ring Count 43.0

Amide Bonds 204.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0280263 VERIFIED: NO

Provenance & Taxonomy

OrganismCorythaixoides concolor [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria