Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC433H705N121O132S14

DescriptionStandard

        MKPMSIACAVTVIIACMCVLQSAAVPFPESEVRLEEPVESEAAQSLDQGEAAALVKETSPEVLFRTKRQSHLSLCRYCCNCCKNKGCGFCCRF
    

Molecular Weight10166.87 Da

Isoelectric Point (pI)6.54

Net Charge (pH 7.0)-0.50

Net Charge (pH 7.4) -0.95

Charge Density (pH 7.0) -0.0054

GRAVY Index0.17

Hydrophobic Moment 0.57

Boman Index0.04

Instability Index77.48

Aliphatic Index 77.63

Aromaticity 0.0538

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 2115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4039.15

LogP -43.18

H-bond Donors 149.0

H-bond Acceptors 147.0

Rotatable Bonds 336.0

Heavy Atoms 700.0

Ring Count 11.0

Amide Bonds 98.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0363172 VERIFIED: NO

Provenance & Taxonomy

OrganismPangasianodon hypophthalmus [Animal]

FamilyHepcidin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal