Peptide Database

Peptide NameCathelicidin antimicrobial peptide [Cleaved into: Antibacterial peptide FALL-39 (FALL-39 peptide antibiotic); Antibacterial peptide LL-37]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length170 amino acids

Chemical FormulaC834H1370N240O248S7

DescriptionStandard

        MKTQRDSPSLGRWSLVLLLLGLVMPLAIVAQVLSYQEAVLRAIDGINQRSSDANLYRLLDLDPRPTMDGDPDTPKPVSFTVKETVCPRTTQKSPEDCDFKEDGLVKRCVGTVILNQARDSFDISCDKDNRRFARLGNFFRKVKEKIGGGLKKVGQKIKDFLGNLVPRTAS
    

Molecular Weight18951.71 Da

Isoelectric Point (pI)9.39

Net Charge (pH 7.0)6.48

Net Charge (pH 7.4) 6.16

Charge Density (pH 7.0) 0.0381

GRAVY Index-0.35

Hydrophobic Moment 0.76

Boman Index-0.10

Instability Index34.14

Aliphatic Index 90.53

Aromaticity 0.0588

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7928.52

LogP -87.43

H-bond Donors 278.0

H-bond Acceptors 262.0

Rotatable Bonds 642.0

Heavy Atoms 1329.0

Ring Count 21.0

Amide Bonds 182.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0256276 VERIFIED: YES

Provenance & Taxonomy

OrganismPapio papio [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-MRSA Antibiofilm Antifungal Anti-Candida Anti-Gram-negative Hemolytic

TargetBacillus megaterium

RECORD: Rec_0285194 VERIFIED: YES