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MYP_061086
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Basic Information
TI15 (PMAP-36 peptide derivative)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
15 amino acids
C88H159N27O17
Standard
Sequence
TRKRLKKIGKVLKWI
Physicochemical Analysis
1867.37 Da
12.00
6.39
6.20
0.4262
-0.65
0.76
-0.36
2.77
123.33
0.0667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
760.64
-3.07
29.0
24.0
69.0
132.0
2.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0109527 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus 29213
32 μM
MIC
PMID27251456 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27251456/
RECORD: Rec_0115398 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli ATCC 25922
8 μM
MIC
PMID27251456 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27251456/
RECORD: Rec_0129151 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes
>128 μM
Hemolysis
PMID27251456 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27251456/
RECORD: Rec_0153331 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli EC183
4 μM
MBC
PMID27251456 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27251456/
RECORD: Rec_0154614 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
human red blood cells
PMID27251456 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27251456/
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