Peptide Database

Peptide NameCom7

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC55H77N19O9S2

DescriptionStandard

        CRRWWRFC
    

Molecular Weight1212.45 Da

Isoelectric Point (pI)10.41

Net Charge (pH 7.0)2.74

Net Charge (pH 7.4) 2.51

Charge Density (pH 7.0) 0.3425

GRAVY Index-0.94

Hydrophobic Moment 0.92

Boman Index-0.53

Instability Index151.95

Aliphatic Index 0.00

Aromaticity 0.3750

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 484.30

LogP -1.87

H-bond Donors 22.0

H-bond Acceptors 14.0

Rotatable Bonds 35.0

Heavy Atoms 85.0

Ring Count 5.0

Amide Bonds 7.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0394616 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

C-TermAmidation

Disulfide1-8

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-positive

TargetStaphylococcus aureus

Activity1.9 μM

MethodLD99.99

Half-LifeHuman serum, in vitro; 23400 s

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