Peptide Database

Peptide NameCathelicidin-1 (1-23), CATH-1 (1-23), Fowlicidin-1 (1-23)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC130H214N38O28

DescriptionStandard

        RVKRVWPLVIRTVIAGYNLYRAI
    

Molecular Weight2757.33 Da

Isoelectric Point (pI)11.57

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.55

Charge Density (pH 7.0) 0.2068

GRAVY Index0.43

Hydrophobic Moment 0.78

Boman Index0.06

Instability Index11.44

Aliphatic Index 143.91

Aromaticity 0.1304

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1087.92

LogP -4.85

H-bond Donors 41.0

H-bond Acceptors 33.0

Rotatable Bonds 87.0

Heavy Atoms 196.0

Ring Count 5.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0110692 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

Targethuman red blood cells

Activity38 μM

MethodHemolysis

RECORD: Rec_0160941 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetListeria monocytogenes ATCC 19115

Activity2.3 μM

MethodMIC

RECORD: Rec_0231704 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetStaphylococcus aureus ATCC 25923

Activity1.1 μM

MethodMIC

RECORD: Rec_0238422 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli ATCC 25922

Activity4.5 μM

MethodMIC

RECORD: Rec_0288674 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetSalmonella enterica subsp. enterica serovar Typhimurium ATCC 14028

Activity2.3 μM

MethodMIC