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MYP_060905
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Anti-HIV
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
4 amino acids
C24H50N12O5
Standard
Sequence
RRKK
Physicochemical Analysis
586.73 Da
12.00
3.76
3.55
0.9395
-4.20
0.40
-2.02
150.70
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
326.46
-3.36
13.0
9.0
23.0
41.0
0.0
3.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0301146 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa ATCC 9027
64 μg/mL
MIC
PMID33003569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33003569/
RECORD: Rec_0310462 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Signal peptide
9606;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor
Vaccinia virus (Virus entry); HeLa
2.567 mOD/min
Plaque assay
PaperInhibition of Vaccinia virus entry by a broad spectrum antiviral peptide. | Altmann SE, Jones JC, Schultz-Cherry S, Brandt CR. | Virology. 2009 | PMID:19395056 PMID19395056 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19395056/
RECORD: Rec_0337804 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Signal peptide
9606;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor
Influenza A virus (Virus entry); MDCK
0 %
Hemagglutinin assay
PaperIdentification of the minimal active sequence of an anti-influenza virus peptide. | Jones JC, Settles EW, Brandt CR, Schultz-Cherry S. | Antimicrob Agents Chemother. 2011 | PMID:21220525 PMID21220525 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21220525/
RECORD: Rec_0341942 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida tropicalis PCM 2709-FY
8 μg/mL
MIC
PMID33003569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33003569/
RECORD: Rec_0346033 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Yarrowia lipolytica PCM 2680-FY
8 μg/mL
MIC
PMID33003569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33003569/
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