Peptide Database

Peptide NameSLAY-screened peptide P337

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC114H177N29O33

DescriptionStandard

        VHTLQTYKDAALDTLYRVLFN
    

Molecular Weight2481.80 Da

Isoelectric Point (pI)6.72

Net Charge (pH 7.0)-0.18

Net Charge (pH 7.4) -0.45

Charge Density (pH 7.0) -0.0086

GRAVY Index-0.01

Hydrophobic Moment 0.60

Boman Index0.06

Instability Index6.25

Aliphatic Index 111.43

Aromaticity 0.1429

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1023.85

LogP -7.64

H-bond Donors 36.0

H-bond Acceptors 34.0

Rotatable Bonds 79.0

Heavy Atoms 176.0

Ring Count 4.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0241244 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/