Peptide Database

Peptide NameJ20 (galanin analogue)

Function Ontology

Neurological / Signaling ▸ Neuropeptide activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC99H160N32O27

DescriptionStandard

        RGRGNWTLNSAGYLLGPAAKK
    

Molecular Weight2230.53 Da

Isoelectric Point (pI)11.10

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.1789

GRAVY Index-0.66

Hydrophobic Moment 0.35

Boman Index-0.08

Instability Index-9.57

Aliphatic Index 70.00

Aromaticity 0.0952

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 975.03

LogP -11.10

H-bond Donors 35.0

H-bond Acceptors 31.0

Rotatable Bonds 72.0

Heavy Atoms 158.0

Ring Count 4.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0231378 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor agonist Neuropeptide activity Signaling peptide

TargetGAL1 receptor (Human); GAL2 receptor (Human); GAL3 receptor (Human)

Activity25 nM

MethodKi