Peptide Database

Peptide NameMelittin [P14C]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC129H226N38O32S

DescriptionStandard

        GIGAVLKVLTTGLCALISWIKRKRQQ
    

Molecular Weight2853.47 Da

Isoelectric Point (pI)11.11

Net Charge (pH 7.0)4.75

Net Charge (pH 7.4) 4.53

Charge Density (pH 7.0) 0.1826

GRAVY Index0.43

Hydrophobic Moment 0.56

Boman Index0.11

Instability Index29.92

Aliphatic Index 135.00

Aromaticity 0.0385

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1155.34

LogP -9.06

H-bond Donors 43.0

H-bond Acceptors 38.0

Rotatable Bonds 99.0

Heavy Atoms 200.0

Ring Count 2.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0057528 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyMelittin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetStaphylococcus aureus ATCC 29213

Activity62.5 μM

MethodMIC

RECORD: Rec_0058978 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyMelittin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetPseudomonas aeruginosa ATCC 27853

Activity125 μM

MethodMIC

RECORD: Rec_0106915 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyMelittin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

Targethuman erythrocytes

Activity2.5 μM

MethodHemolysis

RECORD: Rec_0157714 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyMelittin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli ATCC 25922

Activity125 μM

MethodMIC

RECORD: Rec_0307496 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyMelittin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetStaphylococcus aureus ATCC 43300

Activity62.5 μM

MethodMIC