Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length61 amino acids

Chemical FormulaC284H464N74O78S2

DescriptionStandard

        MNISWQSASRVIDAVNAGASIWGIVSIIVAGGGILGMGYAALALLVKKKVKDLGETAAIAW
    

Molecular Weight6227.30 Da

Isoelectric Point (pI)9.40

Net Charge (pH 7.0)1.50

Net Charge (pH 7.4) 1.27

Charge Density (pH 7.0) 0.0246

GRAVY Index0.83

Hydrophobic Moment 0.66

Boman Index0.38

Instability Index24.86

Aliphatic Index 129.67

Aromaticity 0.0656

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 17990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2405.45

LogP -19.13

H-bond Donors 85.0

H-bond Acceptors 82.0

Rotatable Bonds 207.0

Heavy Atoms 438.0

Ring Count 7.0

Amide Bonds 63.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0356018 VERIFIED: NO

Provenance & Taxonomy

OrganismPaenibacillus larvae subsp. pulvifaciens [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Configcyclic peptide topology reported [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal