Peptide Database

Peptide Name[des-Gln14]ghrelin

Function Ontology

Neurological / Signaling ▸ Neuropeptide activity

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC136H227N45O39

DescriptionStandard

        GSSFLSPEHQRVQRKESKKPPAKLQPR
    

Molecular Weight3116.54 Da

Isoelectric Point (pI)11.07

Net Charge (pH 7.0)4.85

Net Charge (pH 7.4) 4.59

Charge Density (pH 7.0) 0.1796

GRAVY Index-1.61

Hydrophobic Moment 0.52

Boman Index-0.47

Instability Index68.56

Aliphatic Index 43.33

Aromaticity 0.0370

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1388.01

LogP -16.56

H-bond Donors 47.0

H-bond Acceptors 45.0

Rotatable Bonds 105.0

Heavy Atoms 220.0

Ring Count 6.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0166598 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Other ModsThe third residue, a serine, is octanoylated.

Bio-Activity Profile

Function

Neuropeptide activity Signaling peptide

Targetghrelin receptor (Human)