Peptide Database

Peptide NameAlpha-defensin 7 (Defensin-related cryptdin-7)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC442H720N130O147S9

DescriptionStandard

        MKTLILLSALVLLAFQVQADPIQNTDEETKTEEQPGEDDQAVSVSFGDPEGSSLQEESLRDLVCYCRTRGCKRREHMNGTCRKGHLMYTLCCR
    

Molecular Weight10495.81 Da

Isoelectric Point (pI)5.08

Net Charge (pH 7.0)-4.36

Net Charge (pH 7.4) -4.79

Charge Density (pH 7.0) -0.0469

GRAVY Index-0.52

Hydrophobic Moment 0.59

Boman Index-0.14

Instability Index47.11

Aliphatic Index 74.41

Aromaticity 0.0430

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4516.56

LogP -51.63

H-bond Donors 162.0

H-bond Acceptors 154.0

Rotatable Bonds 358.0

Heavy Atoms 728.0

Ring Count 9.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0276394 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic

TargetNo Target Organism Found