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MYP_060543
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Basic Information
Beta-defensin
Antimicrobial
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
70 amino acids
C348H555N97O96S9
Standard
Sequence
MTQLLLLIVALLALGHMQPGRSEFKRCWKGQGACRTYCTRQETYLHMCPDASLCCLPYGSRPLSSKPEYV
Physicochemical Analysis
7922.31 Da
8.86
3.62
3.20
0.0517
-0.09
0.55
0.03
53.39
80.86
0.0857
11460.00
11835.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3072.53
-27.67
114.0
111.0
255.0
550.0
14.0
73.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0116409 VERIFIED: NO
Provenance & Taxonomy
Canis lupus familiaris [Animal]
Defensin
9615
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal
Qualitative functional evidence
PaperCross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract PMID16033865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16033865/; https://www.uniprot.org/uniprotkb/Q30KT0/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0296596 VERIFIED: NO
Provenance & Taxonomy
Nyctereutes procyonoides (Raccoon dog) [Animal]
Defensin
Structure & Mods
disulfide-stabilized linear peptide scaffold [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Defensin
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A811XXH1/entry
RECORD: Rec_0340103 VERIFIED: NO
Provenance & Taxonomy
Canis lupus dingo [Animal]
Defensin
Structure & Mods
disulfide-stabilized linear peptide scaffold [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Defensin
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A8C0QUY4/entry
RECORD: Rec_0363068 VERIFIED: NO
Provenance & Taxonomy
Vulpes vulpes [Bacterium]
Defensin
9627
Structure & Mods
linear polypeptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Defensin Non-hemolytic
Qualitative functional evidence
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A3Q7R8Z3/entry
RECORD: Rec_0385680 VERIFIED: NO
Provenance & Taxonomy
Canis lupus familiaris (Dog) [Animal]
Defensin
Structure & Mods
disulfide-stabilized linear peptide scaffold [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Defensin
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A8C0TGW6/entry