Peptide Database

Peptide NameDefensin 3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC354H573N107O97S10

DescriptionStandard

        MGRKTLSFLFMLFLLLAADVTVKTAEARKCAAQSHRFKGACVRDSNCKTVCLIEGFSGGDCHGFRRRCFCTKSC
    

Molecular Weight8200.65 Da

Isoelectric Point (pI)9.41

Net Charge (pH 7.0)7.60

Net Charge (pH 7.4) 7.15

Charge Density (pH 7.0) 0.1027

GRAVY Index0.11

Hydrophobic Moment 0.54

Boman Index-0.03

Instability Index53.43

Aliphatic Index 67.30

Aromaticity 0.0946

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3309.38

LogP -35.94

H-bond Donors 129.0

H-bond Acceptors 117.0

Rotatable Bonds 278.0

Heavy Atoms 568.0

Ring Count 9.0

Amide Bonds 75.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0091672 VERIFIED: NO

Provenance & Taxonomy

OrganismLens culinaris [Bacterium]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicidal Non-hemolytic Non-ribosomal