Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length145 amino acids

Chemical FormulaC711H1172N180O202S7

DescriptionStandard

        MMKLLVKTVKTPIITFEPNNATVQSLASVTAYAIQPNATLTPLFVLNLDSSVSARVFVSGTRLAGAVTLNKMDLTLGTSYVGDFQVSSLDNIFQMVLKMVVIPRLNAQLAKGYPLPTLGKMKLVNTQLLVLKDHLMIGTDVQFTG
    

Molecular Weight15698.45 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)4.58

Net Charge (pH 7.4) 4.30

Charge Density (pH 7.0) 0.0316

GRAVY Index0.45

Hydrophobic Moment 0.64

Boman Index0.21

Instability Index22.91

Aliphatic Index 116.21

Aromaticity 0.0621

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6094.41

LogP -54.85

H-bond Donors 207.0

H-bond Acceptors 215.0

Rotatable Bonds 520.0

Heavy Atoms 1100.0

Ring Count 17.0

Amide Bonds 159.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0203071 VERIFIED: YES

Provenance & Taxonomy

OrganismNotothenia coriiceps [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria