Peptide Database

Peptide NameSLAY-screened peptide P3796

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC108H175N29O23S

DescriptionStandard

        MLAILFTLNARRPFHAPVVI
    

Molecular Weight2279.79 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)1.59

Net Charge (pH 7.4) 1.32

Charge Density (pH 7.0) 0.0794

GRAVY Index1.10

Hydrophobic Moment 0.42

Boman Index0.35

Instability Index86.29

Aliphatic Index 141.50

Aromaticity 0.1000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 814.44

LogP -2.79

H-bond Donors 28.0

H-bond Acceptors 27.0

Rotatable Bonds 69.0

Heavy Atoms 161.0

Ring Count 5.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0036710 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/