Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length184 amino acids

Chemical FormulaC926H1410N210O290S7

DescriptionStandard

        QIDDLAEVDYSLSGLPAVFQPFIDLDLKGIVFPAGNHTDSPYVAASFTIPDQSDSMLYLAFSEYFFQTSSFAYYTTGAFNMTIAEETCSYFNINTEIFSSIIPEVAKYSVTPYPVMLKLMSTEIPTISLQQDSFTVEIQGSVEVLAILPDSTTQSLFTLNIAANTSISLNIFDQKLMSSLCLNR
    

Molecular Weight20348.79 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-15.15

Net Charge (pH 7.4) -15.47

Charge Density (pH 7.0) -0.0823

GRAVY Index0.26

Hydrophobic Moment 0.55

Boman Index0.23

Instability Index52.18

Aliphatic Index 94.89

Aromaticity 0.1250

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7944.95

LogP -90.05

H-bond Donors 270.0

H-bond Acceptors 283.0

Rotatable Bonds 651.0

Heavy Atoms 1433.0

Ring Count 34.0

Amide Bonds 200.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0180298 VERIFIED: NO

Provenance & Taxonomy

OrganismPheucticus melanocephalus (Black-headed grosbeak) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria