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MYP_060347
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Basic Information
H4
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
29 amino acids
C174H295N49O35
Standard
Sequence
KFKKLFKKLSPVIGKEFKRIVERIKRFLR
Physicochemical Analysis
3633.51 Da
11.62
9.76
9.54
0.3365
-0.50
1.10
-0.31
30.39
100.69
0.1379
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1419.92
-5.52
52.0
45.0
133.0
258.0
5.0
28.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0240212 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
MRSA
5-10 μM
MIC
PaperHybridization and antibiotic synergism as a tool for reducing the cytotoxicity of antimicrobial peptides
RECORD: Rec_0250567 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
10 μM
MIC
PMID29910626 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29910626/
RECORD: Rec_0254606 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
E. faecium VRE
5 μM
MIC
PaperHybridization and antibiotic synergism as a tool for reducing the cytotoxicity of antimicrobial peptides
RECORD: Rec_0256838 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
HEK293
PMID29910626 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29910626/
RECORD: Rec_0279173 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Klebsiella pneumoniae ATCC 13883
2.5 μM
MIC
PaperHybridization and antibiotic synergism as a tool for reducing the cytotoxicity of antimicrobial peptides
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