Peptide Database

Peptide NameInterleukin-10

Function Ontology

Antimicrobial ▸ Antibacterial

Immunology ▸ Chemokine signaling ▸ Chemokine-like peptide

Immunology ▸ Immune modulation ▸ Cytokine modulation

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length160 amino acids

Chemical FormulaC823H1302N228O244S11

DescriptionStandard

        SPGQGTQSENSCTHFPGNLPNMLRDLRDAFSRVKTFFQMKDQLDNLLLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENQDPDIKAHVNSLGENLKTLRLRLRRCHRFLPCENKSKAVEQVKNAFNKLQEKGIYKAMSEFDIFINYIEAYMTMKIRN
    

Molecular Weight18647.24 Da

Isoelectric Point (pI)7.63

Net Charge (pH 7.0)0.71

Net Charge (pH 7.4) 0.24

Charge Density (pH 7.0) 0.0044

GRAVY Index-0.57

Hydrophobic Moment 0.82

Boman Index-0.11

Instability Index56.43

Aliphatic Index 77.44

Aromaticity 0.0938

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7700.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7734.53

LogP -73.29

H-bond Donors 264.0

H-bond Acceptors 259.0

Rotatable Bonds 642.0

Heavy Atoms 1306.0

Ring Count 24.0

Amide Bonds 181.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0168984 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyIL-10 family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide12-108; 62-114

Bio-Activity Profile

Function

Cytokine Growth factor IL-10 family Antibacterial Chemokine-like Growth factor signaling Host defense