Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition

Enzyme modulation ▸ Enzyme inhibition ▸ Integrase inhibition

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC160H250N44O39S

DescriptionStandard

        RMIYKNILFYLVPGPGHGAEPERRNIKYL
    

Molecular Weight3446.03 Da

Isoelectric Point (pI)9.82

Net Charge (pH 7.0)2.85

Net Charge (pH 7.4) 2.58

Charge Density (pH 7.0) 0.0982

GRAVY Index-0.44

Hydrophobic Moment 0.54

Boman Index-0.02

Instability Index91.69

Aliphatic Index 94.14

Aromaticity 0.1379

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1339.64

LogP -7.33

H-bond Donors 46.0

H-bond Acceptors 44.0

Rotatable Bonds 110.0

Heavy Atoms 244.0

Ring Count 8.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0411437 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetHIV-1 integrase

Activity85 μM

MethodIC50

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