Peptide Database

Peptide NameNL6-Y3A

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition

Enzyme modulation ▸ Enzyme inhibition ▸ Integrase inhibition

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC65H103N17O14

DescriptionStandard

        TAAFLLKLAGRW
    

Molecular Weight1346.62 Da

Isoelectric Point (pI)11.00

Net Charge (pH 7.0)1.40

Net Charge (pH 7.4) 1.21

Charge Density (pH 7.0) 0.1164

GRAVY Index0.77

Hydrophobic Moment 0.48

Boman Index0.29

Instability Index42.75

Aliphatic Index 122.50

Aromaticity 0.1667

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 507.36

LogP -1.70

H-bond Donors 19.0

H-bond Acceptors 16.0

Rotatable Bonds 42.0

Heavy Atoms 96.0

Ring Count 3.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0404182 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetHIV-1 integrase

Activity193±10 μM

MethodIC50

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