Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC192H301N51O58S

DescriptionStandard

        LGEWYNQTKELQQKFYEIIMNIEQNNVQVKKGLQQ
    

Molecular Weight4283.82 Da

Isoelectric Point (pI)6.29

Net Charge (pH 7.0)-0.23

Net Charge (pH 7.4) -0.45

Charge Density (pH 7.0) -0.0067

GRAVY Index-1.00

Hydrophobic Moment 0.58

Boman Index-0.13

Instability Index68.62

Aliphatic Index 83.43

Aromaticity 0.1143

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1856.47

LogP -15.93

H-bond Donors 59.0

H-bond Acceptors 59.0

Rotatable Bonds 152.0

Heavy Atoms 302.0

Ring Count 5.0

Amide Bonds 45.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0229968 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 94.3%, E 0.0%, T 0.0%, C 5.7% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Antimicrobial

RECORD: Rec_0256518 VERIFIED: YES

Provenance & Taxonomy

OrganismFeline immunodeficiency virus [Virus]

FamilyVirus-derived peptide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Entry inhibitor Fusion inhibitor

TargetFeline immunodeficiency virus (Virus entry); HeLa

MethodSyncytia assay

PaperAntiviral activity of membrane fusion inhibitors that target gp40 of the feline immunodeficiency virus envelope protein. | Mizukoshi F, Baba K, Goto Y, Setoguchi A, Fujino Y, Ohno K, Oishi S, Kodera Y, Fujii N, Tsujimoto H. | Vet Microbiol. 2009 | PMID:19036536 PMID19036536 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19036536/