Peptide Database

Peptide NameBitter peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Sensory / Food function ▸ Taste-active peptide

Standard StatusStandard

Sequence Length2 amino acids

Chemical FormulaC10H18N2O3

DescriptionStandard

PV

Molecular Weight214.26 Da

Isoelectric Point (pI)5.96

Net Charge (pH 7.0)-0.04

Net Charge (pH 7.4) -0.10

Charge Density (pH 7.0) -0.0208

GRAVY Index1.30

Hydrophobic Moment 0.53

Boman Index0.60

Instability Index101.30

Aliphatic Index 145.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 78.43

LogP -0.04

H-bond Donors 3.0

H-bond Acceptors 3.0

Rotatable Bonds 4.0

Heavy Atoms 15.0

Ring Count 1.0

Amide Bonds 1.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0035204 VERIFIED: YES

Provenance & Taxonomy

OrganismHordeum vulgare [Plant]

Tax ID4513

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Taste

RECORD: Rec_0107753 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyCasein-derived peptide

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Taste

RECORD: Rec_0236593 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/

RECORD: Rec_0375915 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antidiabetic DPP-IV inhibitory

Targethuman dipeptidyl peptidase IV