Peptide Database

Peptide NameInsulin-1 A chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC103H157N29O33S4

DescriptionStandard

        GIVEQCCHRPCSIFELENYCN
    

Molecular Weight2457.78 Da

Isoelectric Point (pI)4.75

Net Charge (pH 7.0)-2.18

Net Charge (pH 7.4) -2.50

Charge Density (pH 7.0) -0.1040

GRAVY Index-0.14

Hydrophobic Moment 0.44

Boman Index0.02

Instability Index28.12

Aliphatic Index 69.52

Aromaticity 0.0952

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1008.74

LogP -10.23

H-bond Donors 37.0

H-bond Acceptors 36.0

Rotatable Bonds 78.0

Heavy Atoms 169.0

Ring Count 4.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0358034 VERIFIED: NO

Provenance & Taxonomy

OrganismKatsuwonus pelamis [Animal]

FamilyInsulin

Tax ID8226

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-11

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour