Peptide Database

Peptide NameAurein-2.4

Function Ontology

Anticancer

Anticancer ▸ Antitumor

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Enzyme modulation ▸ Enzyme inhibition ▸ nNOS inhibitor

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC69H118N16O18

DescriptionStandard

        FDIVKKVVGTIAGL
    

Molecular Weight1459.77 Da

Isoelectric Point (pI)8.59

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0542

GRAVY Index1.23

Hydrophobic Moment 0.60

Boman Index0.42

Instability Index-8.21

Aliphatic Index 152.86

Aromaticity 0.0714

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 551.19

LogP -2.55

H-bond Donors 19.0

H-bond Acceptors 19.0

Rotatable Bonds 49.0

Heavy Atoms 103.0

Ring Count 1.0

Amide Bonds 13.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0270808 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria aurea [Animal]

FamilyAurein

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anticancer Antitumor Anti-Gram-positive

TargetStreptococcus uberis

RECORD: Rec_0276819 VERIFIED: YES