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MYP_060082
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Basic Information
Perinerin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Fungicidal activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
51 amino acids
C257H421N87O68S5
Standard
Sequence
FNKLKQGSSKRTCAKCFRKIMPSVHELDERRRGANRWAAGFRKCVSSICRY
Physicochemical Analysis
5977.96 Da
10.66
10.81
10.48
0.2119
-0.80
0.83
-0.35
64.89
49.80
0.0980
6990.00
7240.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2588.10
-29.10
100.0
85.0
206.0
417.0
8.0
53.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0105089 VERIFIED: YES
Provenance & Taxonomy
Nereis aibuhitensis [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Bacillus megaterium
PaperPubMed PMID: 15113828 PMID15113828 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15113828/
RECORD: Rec_0107391 VERIFIED: YES
Provenance & Taxonomy
Perinereis aibuhitensis [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Micrococcus luteus
PMID15113828 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15113828/
RECORD: Rec_0113854 VERIFIED: YES
Provenance & Taxonomy
Nereis aibuhitensis [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Pseudomonas aeruginosa
PaperPubMed PMID: 15113828 PMID15113828 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15113828/
RECORD: Rec_0207187 VERIFIED: YES
Provenance & Taxonomy
Asian marine clamworms [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Perinerin has marked activity
<15 μg/mL
MIC
PaperPerinerin, a novel antimicrobial peptide purified from the clamworm Perinereis aibuhitensis grube and its partial characterization.
RECORD: Rec_0229894 VERIFIED: YES
Provenance & Taxonomy
Asian marine clamworms [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Bacillus megaterium
1.5-5 μg/mL
MIC
PaperPerinerin, a novel antimicrobial peptide purified from the clamworm Perinereis aibuhitensis grube and its partial characterization.
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