Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length65 amino acids

Chemical FormulaC336H528N86O87S8

DescriptionStandard

        MKPFLVTLAVLLLFFQVTAAVGSIEKCWNYHGSCRDECLKNEKVYVFCMSGKLCCLRPKDQPHLP
    

Molecular Weight7420.83 Da

Isoelectric Point (pI)8.60

Net Charge (pH 7.0)2.62

Net Charge (pH 7.4) 2.20

Charge Density (pH 7.0) 0.0403

GRAVY Index0.22

Hydrophobic Moment 0.43

Boman Index0.12

Instability Index54.12

Aliphatic Index 91.38

Aromaticity 0.1077

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2744.10

LogP -18.73

H-bond Donors 99.0

H-bond Acceptors 100.0

Rotatable Bonds 241.0

Heavy Atoms 517.0

Ring Count 14.0

Amide Bonds 68.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0418902 VERIFIED: NO

Provenance & Taxonomy

OrganismChlorocebus sabaeus [Animal]

FamilyBeta-defensin; Defensin

Tax ID60711

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic