Peptide Database

Peptide NameGlicentin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC345H551N109O117S2

DescriptionStandard

        RSLQDTEEKPRSVSASQTDMLDDPDQMNEDKRHSQGTFTSDYSKYLDSRRAQQFLKWLLNVKRNRNNIA
    

Molecular Weight8161.86 Da

Isoelectric Point (pI)8.31

Net Charge (pH 7.0)0.86

Net Charge (pH 7.4) 0.58

Charge Density (pH 7.0) 0.0124

GRAVY Index-1.41

Hydrophobic Moment 0.70

Boman Index-0.41

Instability Index77.78

Aliphatic Index 52.32

Aromaticity 0.0725

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3799.92

LogP -48.41

H-bond Donors 132.0

H-bond Acceptors 121.0

Rotatable Bonds 282.0

Heavy Atoms 573.0

Ring Count 9.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0038724 VERIFIED: NO

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyGlucagon

Tax ID10141

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0259971 VERIFIED: YES

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyGlicentin

Tax ID10141

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Other Mods34:Phosphoserine

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation Receptor modulation

Half-LifeMammalian: 1 hour; Yeast: 2 min; E. coli: 2 min

RECORD: Rec_0323101 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/