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MYP_060012
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Basic Information
Bowman-Birk type proteinase inhibitor, BBI
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
71 amino acids
C316H492N90O115S15
Standard
Sequence
DDESSKPCCDQCACTKSNPPQCRCSDMRLNSCHSACKSCICALSYPAQCFCVDITDFCYEPCKPSEDDKEN
Physicochemical Analysis
7872.80 Da
4.51
-5.28
-5.76
-0.0743
-0.63
0.47
-0.18
54.07
31.69
0.0563
2980.00
3855.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3299.29
-46.05
123.0
126.0
253.0
536.0
11.0
76.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0106801 VERIFIED: YES
Provenance & Taxonomy
Glycine max [Plant]; Glycine soja [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans DAY185
20 μM
MIC
PMID29062897;19885848 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29062897/
RECORD: Rec_0159613 VERIFIED: YES
Provenance & Taxonomy
Glycine max [Plant]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 19885848 PMID19885848 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19885848/
RECORD: Rec_0208354 VERIFIED: YES
Provenance & Taxonomy
Glycine max [Plant]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
HT-29
48.3±3.5 μM
IC50
PaperPubMed PMID: 19885848 PMID19885848 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19885848/
RECORD: Rec_0263422 VERIFIED: YES
Provenance & Taxonomy
Glycine max [Plant]; Glycine soja [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer Cytotoxic
Human colon adenocarcinoma HT29
48.3
IC50
PMID29062897;19885848 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29062897/
RECORD: Rec_0294994 VERIFIED: YES
Provenance & Taxonomy
Glycine max [Plant]; Glycine soja [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Fusarium graminearum PH-1
10 μM
MIC
PMID29062897;19885848 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29062897/
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