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MYP_060000
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Basic Information
2IQ3
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
23 amino acids
C120H190N34O36S
Standard
Sequence
DNTDSVVKIQSWFRMATARKSYL
Physicochemical Analysis
2717.06 Da
9.70
1.76
1.55
0.0765
-0.51
0.49
-0.15
33.77
67.83
0.1304
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1177.31
-12.21
43.0
39.0
90.0
191.0
4.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0021161 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Candida albicans
Paper抗菌肽2IQ3及其突变体的原核表达与纯化; Prokaryotic expression and purification of antimicrobial peptide 2IQ3 and its mutants. [J].兰州大学学报(医学版),2015,41(03):19-22. DOI:10.13885/j.issn.1000-2812.2015.03.004. Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP37240
RECORD: Rec_0056042 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
26 μM
MIC
PMID23238369 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23238369/
RECORD: Rec_0101698 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans
25 μM
MIC
PaperPubMed PMID: 23238369 PMID23238369 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23238369/
RECORD: Rec_0118932 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus
26 μM
MIC
PaperPubMed PMID: 23238369 PMID23238369 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23238369/
RECORD: Rec_0319214 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
25 μM
MIC
PMID23238369 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23238369/
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