Peptide Database

Peptide NameColicin-D

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length454 amino acids

Chemical FormulaC2121H3389N567O656S16

DescriptionStandard

        MSKESRTLSSRDEEPIINYLGEGKFKFKSQDAACYMHPLGWVADNNRGGISLCFTTEEENCLALFKLTGVQPVPVYTPEMATASSNALKAAGIMALSRAPGAIQFSIAGSGVLTPVTQVASAVSGAIARALAALAATATASTAGPIAAAVVMGMWPSEAGQGSDKWNGQNLALLSLPLTTLSGKQTVLPGRPTIDLPARGSLMMNGNQLEFKLLKTGGALSKAVPVLNAVRDAVTGLDSIIIPAMGGVPERTILINPAPTGPMFPPHTGNSSPKPVTPVHTGTTIETIDKPLILTTPVPDETFDFIYWQLDAKGSGVEPVYVVVSSNGDASKGFNQTEIKIINEAQGILDSKVMDQIQQAHSKGQAVTVVINNRIIQYEPNLPASGMTMFGDNGFYLGPEAFKSKVELQKTVLHELYRLNTSNSGNGVSEALASQETYAAYDFAEKASSTLRSK
    

Molecular Weight47841.04 Da

Isoelectric Point (pI)5.84

Net Charge (pH 7.0)-4.04

Net Charge (pH 7.4) -4.66

Charge Density (pH 7.0) -0.0089

GRAVY Index-0.03

Hydrophobic Moment 0.62

Boman Index0.13

Instability Index34.42

Aliphatic Index 87.51

Aromaticity 0.0617

Extinction Coeff. Reduced 36900.00

Extinction Coeff. Oxidized 37025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0344092 VERIFIED: YES

Provenance & Taxonomy

OrganismPragia fontium [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)