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MYP_059981
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Basic Information
Desotamide A
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
6 amino acids
C35H54N8O8
Standard
Sequence
NGWLLI
Physicochemical Analysis
714.85 Da
5.53
-0.24
-0.44
-0.0400
1.22
0.26
0.67
24.42
195.00
0.1667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
267.70
0.19
9.0
8.0
21.0
51.0
2.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0282075 VERIFIED: YES
Provenance & Taxonomy
Streptomyces scopuliridis SCSIO ZJ46 [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human lung carcinoma NCI-H460
100 μM
IC50
PMID25072108 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25072108/
RECORD: Rec_0304394 VERIFIED: YES
Provenance & Taxonomy
Streptomyces scopuliridis SCSIO ZJ46 [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human breast adenocarcinoma MCF-7
100 μM
IC50
PMID25072108 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25072108/
RECORD: Rec_0305867 VERIFIED: YES
Provenance & Taxonomy
Streptomyces scopuliridis SCSIO ZJ46 [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human hepatocellular carcinoma HepG2
100 μM
IC50
PMID25072108 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25072108/
RECORD: Rec_0317562 VERIFIED: YES
Provenance & Taxonomy
Streptomyces scopuliridis SCSIO ZJ46 [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 29213
16 μg/mL
MIC
PMID25072108 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25072108/
RECORD: Rec_0358541 VERIFIED: YES
Provenance & Taxonomy
Streptomyces scopuliridis [Bacterium]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Hep-G2
100 μM
IC50
PaperPubMed PMID: 25072108 PMID25072108 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25072108/
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