Peptide Database

Peptide NameLt-I4S (Derived from Lt)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC77H129N25O18

DescriptionStandard

        FKRSVQRIKDFLR
    

Molecular Weight1693.00 Da

Isoelectric Point (pI)11.72

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.2892

GRAVY Index-0.85

Hydrophobic Moment 0.87

Boman Index-0.51

Instability Index59.03

Aliphatic Index 82.31

Aromaticity 0.1538

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 750.88

LogP -5.77

H-bond Donors 28.0

H-bond Acceptors 22.0

Rotatable Bonds 60.0

Heavy Atoms 120.0

Ring Count 2.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0379042 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli ATCC 25922

Activity10 μM

MethodMIC

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