Peptide Database

Peptide NamepbpX signal peptide

Function Ontology

Annotation / Sequence feature ▸ Signal peptide

Biotechnology / Production and expression ▸ Secretory enzyme production ▸ Cutinase secretion

Biotechnology / Production and expression ▸ Secretory expression optimization

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC202H356N70O47S3

DescriptionStandard

        MTSPTRRRTAKRRRRKLNKRGKLLFGLLAVMVCITIWNA
    

Molecular Weight4613.62 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)11.49

Net Charge (pH 7.4) 11.25

Charge Density (pH 7.0) 0.2945

GRAVY Index-0.37

Hydrophobic Moment 0.58

Boman Index-0.29

Instability Index110.95

Aliphatic Index 92.56

Aromaticity 0.0513

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1962.73

LogP -18.42

H-bond Donors 76.0

H-bond Acceptors 62.0

Rotatable Bonds 160.0

Heavy Atoms 322.0

Ring Count 4.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0006946 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus subtilis [Bacterium]

FamilyTat signal peptide

Tax ID1423

Structure & Mods

Configlinear signal peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization Cutinase secretion

TargetBacillus subtilis TEB1030

MethodSecretion phenotype assay

PaperBrockmeier U, Caspers M, Freudl R, et al. Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria[J]. Journal of Molecular Biology, 2006, 362(3): 393-402. PMID16930615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16930615/

RECORD: Rec_0092902 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus subtilis [Bacterium]

FamilyTat signal peptide

Tax ID1423

Structure & Mods

Configlinear signal peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization Natto phytase secretion

TargetBacillus subtilis RIK1285

Activity2.57 U/mL

MethodPhytase activity assay