Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length83 amino acids

Chemical FormulaC413H672N112O113S10

DescriptionStandard

        MKISVLLFVLFFFLISLPPGNCGMKDTYSCFIKKGKCRRACHDLETPVSFCTKLNANCCMEKSEVKLSIPEKQNAGNIRKGNK
    

Molecular Weight9335.09 Da

Isoelectric Point (pI)9.35

Net Charge (pH 7.0)7.52

Net Charge (pH 7.4) 7.13

Charge Density (pH 7.0) 0.0906

GRAVY Index-0.08

Hydrophobic Moment 0.59

Boman Index-0.00

Instability Index46.73

Aliphatic Index 78.67

Aromaticity 0.0843

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3642.69

LogP -34.01

H-bond Donors 131.0

H-bond Acceptors 132.0

Rotatable Bonds 319.0

Heavy Atoms 648.0

Ring Count 12.0

Amide Bonds 89.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0388628 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyDefensin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence