Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC436H711N125O146S10

DescriptionStandard

        MKTLILLSALVLLAFQVQADPIQNTDEETKTEEQPGEEDQAVSVSFGDPEGSSLQEESLRDLVCYCRARGCKGRERMNGTCSKGHLMYMLCCR
    

Molecular Weight10360.71 Da

Isoelectric Point (pI)4.77

Net Charge (pH 7.0)-5.44

Net Charge (pH 7.4) -5.83

Charge Density (pH 7.0) -0.0585

GRAVY Index-0.39

Hydrophobic Moment 0.59

Boman Index-0.08

Instability Index46.48

Aliphatic Index 75.48

Aromaticity 0.0430

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4405.75

LogP -49.83

H-bond Donors 157.0

H-bond Acceptors 152.0

Rotatable Bonds 355.0

Heavy Atoms 717.0

Ring Count 8.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0093055 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyDefensin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence