Peptide Database

Peptide NameInvertebrate-type lysozyme 2 (EC 3.2.1.17) (1;4-beta-N-acetylmuramidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length139 amino acids

Chemical FormulaC642H991N187O194S20

DescriptionStandard

        MFVKAILLLSIAVAYASADCLHCICMRESGCKPIGCHMDVGSLSCGYYQIKIPYYEDCGQPGKKHGESTEVAWKRCADDLKCATNCVENYYNRYKHECAGTGQGACEVMARNHNGGPRGCHASGTLGYWKGVHSCCGCS
    

Molecular Weight15074.17 Da

Isoelectric Point (pI)7.86

Net Charge (pH 7.0)1.96

Net Charge (pH 7.4) 1.11

Charge Density (pH 7.0) 0.0141

GRAVY Index-0.23

Hydrophobic Moment 0.58

Boman Index0.03

Instability Index31.52

Aliphatic Index 59.71

Aromaticity 0.0863

Extinction Coeff. Reduced 24410.00

Extinction Coeff. Oxidized 25410.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6057.36

LogP -68.10

H-bond Donors 227.0

H-bond Acceptors 223.0

Rotatable Bonds 491.0

Heavy Atoms 1043.0

Ring Count 25.0

Amide Bonds 146.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0018608 VERIFIED: YES

Provenance & Taxonomy

OrganismCaenorhabditis elegans [Animal]

FamilyGlycosyl hydrolase 22; Type-I lysozyme subfamily

Tax ID6239

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriolytic enzyme Anti-Gram-positive Glycosidase Hydrolase Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)