Peptide Database

Peptide NameBovine beta-defensin 1

Function Ontology

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Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC168H267N55O42S8

DescriptionStandard

        SCRWNMGVCIPISCPGNMRQIGTCFGPRVPCCRRW
    

Molecular Weight3985.78 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)4.40

Net Charge (pH 7.4) 4.11

Charge Density (pH 7.0) 0.1257

GRAVY Index-0.05

Hydrophobic Moment 0.43

Boman Index-0.03

Instability Index85.34

Aliphatic Index 50.00

Aromaticity 0.0857

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1548.60

LogP -16.64

H-bond Donors 61.0

H-bond Acceptors 55.0

Rotatable Bonds 121.0

Heavy Atoms 273.0

Ring Count 9.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0314160 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)