Peptide Database

Peptide NamePalustrin-Ca (Host defense peptide) (HDP)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Listeria

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length71 amino acids

Chemical FormulaC352H574N88O105S4

DescriptionStandard

        MFTLKKSLLLLFFLGTISLSLCEQERDADGDEGEVEEVKRGFLDIIKDTGKEFAVKILNNLKCKLAGGCPP
    

Molecular Weight7847.11 Da

Isoelectric Point (pI)5.02

Net Charge (pH 7.0)-2.51

Net Charge (pH 7.4) -2.80

Charge Density (pH 7.0) -0.0354

GRAVY Index0.03

Hydrophobic Moment 0.74

Boman Index0.06

Instability Index18.40

Aliphatic Index 104.37

Aromaticity 0.0704

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3112.95

LogP -24.59

H-bond Donors 108.0

H-bond Acceptors 107.0

Rotatable Bonds 274.0

Heavy Atoms 549.0

Ring Count 7.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0028412 VERIFIED: YES

Provenance & Taxonomy

OrganismLithobates catesbeianus [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Antilisterial Anti-Gram-negative Anti-Gram-positive Cytotoxic Hemolytic

TargetBacillus subtilis

RECORD: Rec_0144750 VERIFIED: YES

Provenance & Taxonomy

OrganismLithobates catesbeianus [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Antilisterial Anti-Gram-negative Anti-Gram-positive Cytotoxic Hemolytic

TargetListeria spp.

RECORD: Rec_0248352 VERIFIED: YES

Provenance & Taxonomy

OrganismLithobates catesbeianus [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Antilisterial Anti-Gram-negative Anti-Gram-positive Cytotoxic Hemolytic

TargetS. suis

RECORD: Rec_0314949 VERIFIED: YES

Provenance & Taxonomy

OrganismLithobates catesbeianus [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Antilisterial Anti-Gram-negative Anti-Gram-positive Cytotoxic Hemolytic

TargetKlebsiella pneumoniae

RECORD: Rec_0332027 VERIFIED: YES

Provenance & Taxonomy

OrganismLithobates catesbeianus [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Antilisterial Anti-Gram-negative Anti-Gram-positive Cytotoxic Hemolytic

TargetStaphylococcus aureus

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