Peptide Database

Peptide NameNeutrophil cationic antibacterial polypeptide of 11 kDa

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length178 amino acids

Chemical FormulaC895H1467N265O246S8

DescriptionStandard

        MGTPRDAASGGPRLLLPLLLLLLLTPATAWVLSYQQAVQRAVDGINKNLADNENLFRLLSLDTQPPGDNDPYSPKPVSFTIKETVCTKMLQRPLEQCDFKENGLVQRCTGTVTLDSAFNVSSLSCLGGRRFRRMVGLRKKFRKTRKRIQKLGRKIGKTGRKVWKAWREYGQIPYPCRI
    

Molecular Weight20132.37 Da

Isoelectric Point (pI)10.39

Net Charge (pH 7.0)18.46

Net Charge (pH 7.4) 18.13

Charge Density (pH 7.0) 0.1037

GRAVY Index-0.42

Hydrophobic Moment 0.90

Boman Index-0.12

Instability Index33.65

Aliphatic Index 87.08

Aromaticity 0.0730

Extinction Coeff. Reduced 22460.00

Extinction Coeff. Oxidized 22710.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8314.48

LogP -96.63

H-bond Donors 297.0

H-bond Acceptors 273.0

Rotatable Bonds 674.0

Heavy Atoms 1414.0

Ring Count 28.0

Amide Bonds 193.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0330009 VERIFIED: NO

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyCathelicidin

Tax ID10141

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal