Peptide Database

Peptide NameGallinacin-1 alpha (Gal-1 alpha) (Antimicrobial peptide CHP2) (Chicken heterophil peptide 2)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length65 amino acids

Chemical FormulaC332H531N91O79S7

DescriptionStandard

        MRIVYLLLPFILLLAQGAAGSSQALGRKSDCFRKNGFCAFLKCPYLTLISGKCSRFHLCCKRIWG
    

Molecular Weight7285.78 Da

Isoelectric Point (pI)9.82

Net Charge (pH 7.0)8.52

Net Charge (pH 7.4) 8.16

Charge Density (pH 7.0) 0.1311

GRAVY Index0.48

Hydrophobic Moment 0.54

Boman Index0.14

Instability Index24.15

Aliphatic Index 102.15

Aromaticity 0.1231

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2720.62

LogP -20.01

H-bond Donors 104.0

H-bond Acceptors 96.0

Rotatable Bonds 241.0

Heavy Atoms 509.0

Ring Count 12.0

Amide Bonds 67.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0063089 VERIFIED: YES

Provenance & Taxonomy

OrganismGallus gallus [Animal]

FamilyBeta-defensin; Defensin

Tax ID9031

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetListeria monocytogenes (Gram-positive)

RECORD: Rec_0240989 VERIFIED: YES