Peptide Database

Peptide Name[125I]exendin-(9-39)

Function Ontology

Hormonal / Endocrine ▸ Hormonal activity

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Receptor modulation ▸ Antagonist

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC149H233N39O48S

DescriptionStandard

        DLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS
    

Molecular Weight3370.74 Da

Isoelectric Point (pI)4.59

Net Charge (pH 7.0)-2.23

Net Charge (pH 7.4) -2.44

Charge Density (pH 7.0) -0.0719

GRAVY Index-0.65

Hydrophobic Moment 0.71

Boman Index-0.01

Instability Index82.57

Aliphatic Index 66.13

Aromaticity 0.0645

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1384.49

LogP -13.97

H-bond Donors 45.0

H-bond Acceptors 47.0

Rotatable Bonds 108.0

Heavy Atoms 237.0

Ring Count 7.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0226959 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor antagonist Antidiabetic Hormonal activity

TargetGLP-1 receptor (Human)

Activity5 nM

MethodKd