Peptide Database

Peptide NameElapegademase

Function Ontology

Anticancer

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Therapeutic / Biomedical activity ▸ Enzyme replacement therapy

Standard StatusStandard

Sequence Length356 amino acids

Chemical FormulaC1797H2795N477O544S12

DescriptionStandard

        AQTPAFNKPKVELHVHLDGAIKPETILYYGRKRGIALPADTPEELQNIIGMDKPLSLPEFLAKFDYYMPAIAGSREAVKRIAYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQAEGDLTPDEVVSLVNQGLQEGERDFGVKVRSILCCMRHQPSWSSEVVELCKKYREQTVVAIDLAGDETIEGSSLFPGHVKAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTERLGHGYHTLEDTTLYNRLRQENMHFEVCPWSSYLTGAWKPDTEHPVVRFKNDQVNYSLNTDDPLIFKSTLDTDYQMTKNEMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLLYKAYGMPSPA
    

Molecular Weight40170.07 Da

Isoelectric Point (pI)5.40

Net Charge (pH 7.0)-12.21

Net Charge (pH 7.4) -13.15

Charge Density (pH 7.0) -0.0343

GRAVY Index-0.45

Hydrophobic Moment 0.66

Boman Index-0.02

Instability Index40.27

Aliphatic Index 81.04

Aromaticity 0.0899

Extinction Coeff. Reduced 45840.00

Extinction Coeff. Oxidized 46090.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0109685 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyImmunoglobulin

Tax ID9913

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsPEGylation

Bio-Activity Profile

Function

Anticancer Immunomodulatory Enzyme replacement

Half-LifeThis pharmacokinetic property has not been fully studied.

RECORD: Rec_0412490 VERIFIED: NO