Peptide Database

Peptide NameAntimicrobial peptide TsAP-1 (Non-disulfide-bridged peptide 4.22) (NDBP-4.22)

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC382H624N100O106S3

DescriptionStandard

        MQIKHLITLFFLVLIVADQCSAFLSLIPSLVGGSISAFKGRRKREISAQIEQYKDLQKREAELEELLDRLPMY
    

Molecular Weight8409.84 Da

Isoelectric Point (pI)7.89

Net Charge (pH 7.0)0.59

Net Charge (pH 7.4) 0.29

Charge Density (pH 7.0) 0.0081

GRAVY Index0.13

Hydrophobic Moment 0.54

Boman Index0.06

Instability Index43.65

Aliphatic Index 120.27

Aromaticity 0.0822

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3342.44

LogP -23.34

H-bond Donors 117.0

H-bond Acceptors 111.0

Rotatable Bonds 291.0

Heavy Atoms 591.0

Ring Count 9.0

Amide Bonds 77.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0052829 VERIFIED: YES

Provenance & Taxonomy

OrganismTityus serrulatus [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Anticancer Hemolytic

TargetCandida albicans

RECORD: Rec_0191679 VERIFIED: YES

Provenance & Taxonomy

OrganismTityus serrulatus [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Anticancer Hemolytic

TargetEscherichia coli

RECORD: Rec_0258640 VERIFIED: YES

Provenance & Taxonomy

OrganismTityus serrulatus [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Anticancer Hemolytic

TargetStaphylococcus aureus