Peptide Database

Peptide NameC-flanking peptide of NPY

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide Y family

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC146H239N41O50S2

DescriptionStandard

        SSPETLISDLLMRESTGNIPRTRLEDPSMW
    

Molecular Weight3432.83 Da

Isoelectric Point (pI)4.51

Net Charge (pH 7.0)-2.53

Net Charge (pH 7.4) -2.74

Charge Density (pH 7.0) -0.0843

GRAVY Index-0.62

Hydrophobic Moment 0.54

Boman Index-0.12

Instability Index58.79

Aliphatic Index 78.00

Aromaticity 0.0333

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1473.77

LogP -16.57

H-bond Donors 52.0

H-bond Acceptors 50.0

Rotatable Bonds 111.0

Heavy Atoms 239.0

Ring Count 5.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0100368 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus indicus [Animal]

Tax ID9915

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0104963 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyNPY

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

NPY-family Neuropeptide Neuromodulator

RECORD: Rec_0359199 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0361256 VERIFIED: NO

Provenance & Taxonomy

OrganismOvis aries [Animal]

FamilyC-flanking peptide of NPY

Tax ID9940

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Other Mods16:Phosphothreonine

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Reproductive regulator Feeding regulator

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0393968 VERIFIED: NO

Provenance & Taxonomy

OrganismOvis aries [Animal]

FamilyNPY

Tax ID9940

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

NPY-family Neuropeptide Neuromodulator

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