‹ ›
MYP_059706
← PREVIOUS NEXT → BACK
Basic Information
RJ2-Y2,9,16
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
21 amino acids
C108H182N30O25
Standard
Sequence
KYAKKAAKYAKKAAKYAKKAA
Physicochemical Analysis
2300.79 Da
10.30
8.75
8.53
0.4166
-1.09
0.70
-0.34
43.35
42.86
0.1429
4470.00
4470.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
940.19
-6.72
34.0
34.0
83.0
163.0
3.0
20.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0190141 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PaperPubMed PMID: 16923027 PMID16923027 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16923027/
RECORD: Rec_0198519 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
toxicity against Human fibroblasts MRC-5 cells up to 448 μM
448 μM
Cytotoxicity
PaperPubMed PMID: 16923027 PMID16923027 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16923027/
RECORD: Rec_0369517 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 16923027 PMID16923027 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16923027/
RECORD: Rec_0393892 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Herpes simplex virus 1(HSV-1):inhibition of viral entry into Vero cells
146 μM
IC50
PaperPubMed PMID: 16923027 PMID16923027 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16923027/
RECORD: Rec_0426004 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HSV Entry inhibition
Herpes simplex virus 1(HSV-1) | Vero cells
146 μM
IC50
Mammalian: 1.3 h; Yeast: 3 min; E. coli: 2 min
PaperPrediction of activity, synthesis and biological testing of anti-HSV active peptides. | Jenssen H, Gutteberg TJ, Rekdal Ø, Lejon T. | Chem Biol Drug Des. 2006 Jul;68(1):58-66. | DOI:10.1111/j.1747-0285.2006.00412.x | PMID:16923027 PMID16923027 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16923027/