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MYP_059688
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Basic Information
Shep I
Antimicrobial
Antimicrobial ▸ Antifungal
Standard
23 amino acids
C74H99N37O24
Standard
Sequence
GGHGGHGGHGGHGGHGHGGGGHG
Physicochemical Analysis
1890.81 Da
7.25
0.37
-0.19
0.0161
-1.25
0.17
0.21
20.93
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
904.28
-18.07
31.0
31.0
59.0
135.0
7.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0055350 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
APD analysis reveals that this sequence is 82.14% similar to Shepherin I G: 70%, H: 30%. Chemical modification: C-terminal amidation
Bio-Activity Profile
Antimicrobial Antifungal
C. parapsilosis ATCC 22019
6.25 μM
MIC
PaperChemical synthesis, structure-activity relationship, and properties of shepherin I: a fungicidal peptide enriched in glycine-glycine-histidine motifs.
RECORD: Rec_0129369 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
APD analysis reveals that this sequence is 82.14% similar to Shepherin I G: 70%, H: 30%. Chemical modification: C-terminal amidation
Bio-Activity Profile
Antimicrobial Antifungal
C. krusei ATCC 6258
100 μM
MIC
PaperChemical synthesis, structure-activity relationship, and properties of shepherin I: a fungicidal peptide enriched in glycine-glycine-histidine motifs.
RECORD: Rec_0192638 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
APD analysis reveals that this sequence is 82.14% similar to Shepherin I G: 70%, H: 30%. Chemical modification: C-terminal amidation
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans MDM8
12.5 μM
MIC
PaperChemical synthesis, structure-activity relationship, and properties of shepherin I: a fungicidal peptide enriched in glycine-glycine-histidine motifs.
RECORD: Rec_0219362 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
APD analysis reveals that this sequence is 82.14% similar to Shepherin I G: 70%, H: 30%. Chemical modification: C-terminal amidation
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans HU 168
50 μM
MIC
PaperChemical synthesis, structure-activity relationship, and properties of shepherin I: a fungicidal peptide enriched in glycine-glycine-histidine motifs.
RECORD: Rec_0239135 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
APD analysis reveals that this sequence is 82.14% similar to Shepherin I G: 70%, H: 30%. Chemical modification: C-terminal amidation
Bio-Activity Profile
Antimicrobial Antifungal
C. tropicalis Squibb 1600
1.56 μM
MIC
PaperChemical synthesis, structure-activity relationship, and properties of shepherin I: a fungicidal peptide enriched in glycine-glycine-histidine motifs.
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