Peptide Database

Peptide NameSLAY-screened peptide P1930

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC121H177N31O26S

DescriptionStandard

        PPTHYCPNWYRIFRQPLLVL
    

Molecular Weight2513.96 Da

Isoelectric Point (pI)9.37

Net Charge (pH 7.0)2.03

Net Charge (pH 7.4) 1.91

Charge Density (pH 7.0) 0.1017

GRAVY Index-0.22

Hydrophobic Moment 0.69

Boman Index0.09

Instability Index56.35

Aliphatic Index 92.50

Aromaticity 0.2000

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 891.00

LogP -2.80

H-bond Donors 32.0

H-bond Acceptors 30.0

Rotatable Bonds 70.0

Heavy Atoms 179.0

Ring Count 10.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0080966 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/